Metformin — Longevity

Why Metformin

What this treatment offers

Six decades of safety data

One of the most prescribed medications in history, with an extensively documented safety profile.

Metabolic foundation

Improves insulin sensitivity and supports healthy glucose metabolism — cornerstones of metabolic health.

Active longevity research

Metformin is the subject of major aging-research initiatives, including the landmark TAME trial framework studying its potential to target aging biology.

Simple daily protocol

A once- or twice-daily tablet, prescribed and monitored by your provider.

How it works

Care without the waiting room

Start your assessment

A 5-minute online health questionnaire — no appointment, no waiting room.

Provider review

A licensed provider in your state reviews your history and prescribes if appropriate.

Pharmacy ships direct

Your medication ships from a licensed U.S. pharmacy in discreet packaging.

Ongoing support

Message your care team anytime. Dose adjustments and refills handled online.

FAQ

Metformin questions

Why do people take metformin for longevity?

Researchers have observed associations between metformin use and favorable health outcomes beyond diabetes, prompting formal study of its effects on aging biology. It is prescribed off-label for this purpose when a provider determines it's appropriate.

What are common side effects?

Digestive upset is most common, particularly when starting. Taking it with food and gradual dose increases usually help. Your provider will review your kidney function and health history first.

Do I need to have diabetes to qualify?

No — your provider evaluates your metabolic health, labs if available, and goals to determine whether metformin is clinically appropriate for you.

Important safety informationMetformin is available by prescription only after evaluation by a licensed provider. Tell your provider about all medical conditions and medications during your assessment. Individual results vary. This page is educational and is not medical advice.